Research Papers
A curated index of peer-reviewed literature on peptides, with plain-language summaries. All links open to the original source (PubMed, journals, preprints). Research Stack does not host any papers.
Summaries are paraphrased for accessibility. Always read the original paper in full before drawing conclusions. Most studies are preclinical (animal models) unless stated otherwise.
Latest from PubMed
Updated dailyThe most recent therapeutic-peptide publications, retrieved automatically from PubMed. Not editorially curated.
- Treatment strategies for functional hypogonadism in obese men: a systematic review and network meta-analysis
Yang L, He X, et al. · The journal of sexual medicine · 2026
- Quantification of appetite-regulating hormones in children with hypothalamic and common obesity
Gan HW, Leeson C, et al. · Journal of the Endocrine Society · 2026
- The Therapeutic Opportunity of Glucagon-Like Peptide-1 Receptor Agonists in Pediatric Psychiatry
McIntyre RS · Journal of child and adolescent psychopharmacology · 2026
- The effects of cyanoacrylate and concentrated growth factor on wound healing and patient comfort at the palatal donor site: a randomized controlled clinical trial
Altindal D, Sari Can ET, et al. · Clinical oral investigations · 2026
- HIF-1 exerts a double-edged sword regulatory role in hippocampal neuronal PANoptosis of Alzheimer's disease through HK2/VDAC1/NLRP3 axis and RIPK3 signal
Wang S, Luo L, et al. · Pharmacological research · 2026
- Oxidized pullulan/carboxymethyl chitosan hydrogel with salidroside for enhanced wound healing
Fu Y, Chen A, et al. · International journal of biological macromolecules · 2026
- Growth Hormone Receptor Antagonism Extends Lifespan
List EO, Berryman DE, et al. · Aging cell · 2026
- Comparative effectiveness of GLP-1 receptor agonists versus mineralocorticoid receptor antagonists as fourth-line pharmacological therapy in patients with resistant hypertension and overweight or obesity: a retrospective multicenter cohort study in the USA
Tian Z, Willerding JM, et al. · EClinicalMedicine · 2026
- Local Administration of Exendin-4 Ameliorates Wear-Particle-Induced Periprosthetic Osteolysis by Rebalancing Bone Remodeling
Ma B, Peng Z, et al. · Acta biomaterialia · 2026
- Comparative Cardiovascular Outcomes of GLP-1 Receptor Agonists Versus Bariatric Surgery: A Systematic Review and Network Meta-Analysis
Shirmohammadi E, Ghasemloo N, et al. · Endocrinology, diabetes & metabolism · 2026
Editor's Picks — Landmark Studies
Gastrointestinal
Comprehensive review of BPC-157's gastroprotective mechanisms. Covers protection from ethanol, NSAIDs, and stress-induced ulcers in rodent models. Documents NO-pathway involvement and cytoprotective effects across multiple GI tissues.
Musculoskeletal
Rodent study demonstrating accelerated Achilles tendon healing following BPC-157 treatment. Histology showed improved tendon organization and mechanical strength versus control. Established BPC-157 as a promising soft tissue repair agent.
Growth Hormone
Phase I/II human trial demonstrating that CJC-1295 DAC produces sustained GH and IGF-1 elevation for up to 6 days after a single dose. Dose-dependent increases observed. Well tolerated with minimal adverse effects across all dose groups.
Metabolic / GLP-1
Landmark RCT (n=1961) showing that weekly 2.4mg semaglutide resulted in mean body weight reduction of 14.9% vs. 2.4% placebo over 68 weeks. Significant improvements in cardiometabolic risk factors. Established semaglutide as a major advance in obesity pharmacotherapy.
Cardiovascular
Large-scale cardiovascular outcomes trial (n=17,604) demonstrating semaglutide reduced major adverse cardiovascular events by 20% in patients with obesity and established cardiovascular disease. First GLP-1 agonist trial to show cardiovascular benefit independent of diabetes status.
Dermatology / Anti-Aging
Review article summarizing GHK-Cu's role in skin repair. Covers upregulation of collagen I, II, and III synthesis, stimulation of wound contraction, and broad gene regulatory effects affecting over 4,000 human genes. Discusses topical and systemic applications.